This comprehensive report draws from the experiences of the Good Growth Partnership (GGP) to reveal the answers - the conditions, configuration and key design and implementation principles required for an integrated programme to deliver systemic transformation. For almost half a decade the GGP has been implementing an Integrated Supply Chain Approach - working across production, financing, and demand - to improve the sustainability of major agricultural commodities throughout the tropics. Conceived of and funded by the Global Environment Facility and led by the UNDP’s Green Commodities Programme, the programme is implemented in collaboration with Conservation International, the International Finance Corporation, the UN Environment Programme, the World Wildlife Fund and the governments of Indonesia, Paraguay, Brazil and Liberia. This report tackles integrated approaches to commodities transformation at two levels: the conceptual and the operational. First, it outlines why the integrated approach offers better results and value compared to more targeted interventions, and assesses the specific Integrated Supply Chain Approach of the GGP according to established criteria for successful integrated programmes. Then, the report shares lessons from GGP partners and other experts and practitioners of integrated approaches on what it takes to deliver these programmes in reality. These insights are critical to GGP’s future ambitions, as well as to other programmes seeking to drive systemic transformation and reduced deforestation in commodity supply chains and wider food systems.